Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
Product Name : PDK1 polyclonal antibodySequence: Purity: Molecular Weight:Solubility : Appearance: Use/Stability : Description: PDK-1 (Pyruvate dehydrogenase kinase-1) is a 48 kDa protein kinase. It is a member of the mitrochondrial matrix protein kinase family and is related to the histidine protein kinases found in prokaryotes. PDK-1 is responsible for phosphorylation and concomitant inactivation of […]
Product Name : Polyphyllin IDescription:Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis.CAS: 50773-41-6Molecular Weight:855.02Formula: C44H70O16Chemical Name: (2S, 3R, 4R, 5R, 6S)-2-[(2R, 3R, 4S, […]
Product Name : Meloxicam-d3Description:Meloxicam-d3 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.CAS: 942047-63-4Molecular Weight:354.42Formula: C14H13N3O4S2Chemical Name: 4-hydroxy-2-(²H₃)methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2H-1λ⁶,2-benzothiazine-3-carboxamideSmiles : [2H]C([2H])([2H])N1C(=C(O)C2=CC=CC=C2S1(=O)=O)C(=O)NC1=NC=C(C)S1InChiKey: ZRVUJXDFFKFLMG-BMSJAHLVSA-NInChi : InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)/i2D3Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous […]
Product Name : Myeloperoxidase (human leukocytes)Sequence: Purity: ≥98%Molecular Weight:Solubility : Appearance: Green solidUse/Stability : As indicated on product label or CoA when stored as recommended. Stored at -20°C this product is stable for years.Storage of the reconstituted form at 4°C for 2 weeks has no effect on enzyme activity. If solutions must be stored for […]
Product Name : Triazolomethylindole-3-aceticacid-d5Description:Product informationCAS: 1216889-22-3Molecular Weight:261.29Formula: C13H12N4O2Chemical Name: 2-{5-[(1H-1,2,4-triazol-1-yl)(²H₂)methyl](4,6,7-²H₃)-1H-indol-3-yl}acetic acidSmiles : [2H]C1C2C(CC(O)=O)=CNC=2C([2H])=C([2H])C=1C([2H])([2H])N1C=NC=N1InChiKey: KACIHDPNKNLLMA-JZOBIDBQSA-NInChi : InChI=1S/C13H12N4O2/c18-13(19)4-10-5-15-12-2-1-9(3-11(10)12)6-17-8-14-7-16-17/h1-3,5,7-8,15H,4,6H2,(H,18,19)/i1D,2D,3D,6D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of AnalysisStorage Condition : Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Streptomycin} […]
Product Name : LIMK2 monoclonal antibody (10E5-19)Sequence: Purity: Molecular Weight:Solubility : Appearance: Use/Stability : Stable for at least 1 year after receipt when stored at -20°C.Description: The LIM kinases 1 and 2 (LIMK1 and LIMK2) are activated downstream of the Rho-ROCK, Rac-PAK, and Cdc42-MRCK pathways, thereby acting as network nodes in the signaling pathways that […]
Product Name : Xipamide-d6Description:Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE).CAS: 1330262-09-3Molecular Weight:360.85Formula: C15H15ClN2O4SChemical Name: 4-chloro-N-[2,6-di(²H₃)methylphenyl]-2-hydroxy-5-sulfamoylbenzamideSmiles : [2H]C([2H])([2H])C1=CC=CC(=C1NC(=O)C1=CC(=C(Cl)C=C1O)S(N)(=O)=O)C([2H])([2H])[2H]InChiKey: MTZBBNMLMNBNJL-WFGJKAKNSA-NInChi : InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)/i1D3,2D3Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer […]
Product Name : IKK-NBD peptideSequence: Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-GluPurity: ≥95% (HPLC)Molecular Weight:3694.0Solubility : Soluble in DMSO (20mM). Note: This peptide will precipitate when added to tissue culture medium, even to 100µM. However, enough will remain in solution to enter many cell types.Appearance: Lyophilized solidUse/Stability : As indicated on product label or CoA when stored as recommended.Description: NF-κB inhibitor […]
Product Name : pp60 (v-SRC) Autophosphorylation Site, PhosphorylatedDescription:pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification.CAS: 176042-83-4Molecular Weight:Formula: Chemical Name: pp60 (v-SRC) Autophosphorylation Site, PhosphorylatedSmiles : InChiKey: InChi : Purity: ≥98% (or refer […]
Product Name : AmbroxolDescription:Ambroxol (NA-872), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research.CAS: 18683-91-5Molecular Weight:378.10Formula: C13H18Br2N2OChemical Name: 4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-olSmiles : NC1C(Br)=CC(Br)=CC=1CNC1CCC(O)CC1InChiKey: JBDGDEWWOUBZPM-UHFFFAOYSA-NInChi : InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2Purity: ≥98% (or refer […]