Product Name :
WAY-600
CAS No.:
1062159-35-6
Purity :
> 97%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
C1CN(CCO1)C2=NC(=NC3=C2C=N[N]3C4CCN(CC4)CC5=CC=CN=C5)C6=CC7=C([NH]C=C7)C=C6
Product Description :
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308) selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).{{1585973-65-4} web|{1585973-65-4} Technical Information|{1585973-65-4} In Vitro|{1585973-65-4} custom synthesis}
Formula:
C28H30N8O
Molecular Weight :
494.{{2244602-23-9} web|{2244602-23-9} Protocol|{2244602-23-9} In Vitro|{2244602-23-9} supplier} 59
Synonyms:
Additional Information:
|CAS No.PMID:30571037 1062159-35-6 ; |Formula C28H30N8O ; |Molecular Weight 494.59 ; |SMILES C1CN(CCO1)C2=NC(=NC3=C2C=N[N]3C4CCN(CC4)CC5=CC=CN=C5)C6=CC7=C([NH]C=C7)C=C6 ; |Target mTOR ; |Product Description WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308) selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold). ; |Purity > 97% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO