Product Name :
VU-0361737
CAS No.:
1161205-04-4
Purity :
> 98%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
COC1=CC(=CC=C1Cl)NC(=O)C2=NC=CC=C2
Product Description :
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.{{557795-19-4} site|{557795-19-4} Protocol|{557795-19-4} Formula|{557795-19-4} supplier}
Formula:
C13H11ClN2O2
Molecular Weight :
262.{{2992666-48-3} medchemexpress|{2992666-48-3} Biological Activity|{2992666-48-3} Description|{2992666-48-3} custom synthesis} 69
Synonyms:
Additional Information:
|CAS No.PMID:28722873 1161205-04-4 ; |Formula C13H11ClN2O2 ; |Molecular Weight 262.69 ; |SMILES COC1=CC(=CC=C1Cl)NC(=O)C2=NC=CC=C2 ; |Product Description VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displays weak activity at mGlu5 and mGlu8 receptors, is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS. ; |Purity > 98% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO