Product Name :
Tos-PEG5-Boc
Description:
Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
581065-94-3
Molecular Weight:
476.58
Formula:
C22H36O9S
Chemical Name:
tert-butyl 1-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12-tetraoxapentadecan-15-oate
Smiles :
CC1C=CC(=CC=1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C
InChiKey:
GGGJGMGLGUHUMW-UHFFFAOYSA-N
InChi :
InChI=1S/C22H36O9S/c1-19-5-7-20(8-6-19)32(24,25)30-18-17-29-16-15-28-14-13-27-12-11-26-10-9-21(23)31-22(2,3)4/h5-8H,9-18H2,1-4H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{β-Amyloid (1-42), human} MedChemExpress|{β-Amyloid (1-42), human} Neuronal Signaling|{β-Amyloid (1-42), human} Activator|{β-Amyloid (1-42), human} Purity & Documentation|{β-Amyloid (1-42), human} Formula|{β-Amyloid (1-42), human} manufacturer}
Shelf Life:
≥12 months if stored properly.{{LCS-1} site|{LCS-1} Immunology/Inflammation|{LCS-1} Biological Activity|{LCS-1} References|{LCS-1} supplier|{LCS-1} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23880095
Additional information:
Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 581065-94-3|Molecular Weight: 476.58|Formula: C22H36O9S|Chemical Name: tert-butyl 1-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12-tetraoxapentadecan-15-oate|Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCOCCOCCOCCOCCC(=O)OC(C)(C)C|InChiKey: GGGJGMGLGUHUMW-UHFFFAOYSA-N|InChi: InChI=1S/C22H36O9S/c1-19-5-7-20(8-6-19)32(24,25)30-18-17-29-16-15-28-14-13-27-12-11-26-10-9-21(23)31-22(2,3)4/h5-8H,9-18H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|