Product Name :
CSEN Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
4933407H12Rik antibody A type potassium channel modulatory protein 3 antibody A-type potassium channel modulatory protein 3 antibody AI413860 antibody Calsenilin antibody CSEN antibody CSEN_HUMAN antibody DRE antagonist modulator antibody DRE-antagonist modulator antibody DREAM antibody 展开
Function :
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and probably KCND3 trafficking to the cell surface. May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human CSEN 51-150/256
Species reactivity:
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.{{Ropeginterferon alfa-2b} medchemexpress|{Ropeginterferon alfa-2b} Apoptosis|{Ropeginterferon alfa-2b} Protocol|{Ropeginterferon alfa-2b} Description|{Ropeginterferon alfa-2b} custom synthesis|{Ropeginterferon alfa-2b} Cancer} When reconstituted in sterile pH 7.{{Clofarabine} MedChemExpress|{Clofarabine} Autophagy|{Clofarabine} Purity & Documentation|{Clofarabine} Formula|{Clofarabine} supplier|{Clofarabine} Cancer} 4 0.PMID:26644518 01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
28 KDa
Positive control :
Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease.