Product Name :
Biotin-PEG2-NHS ester
Description:
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
596820-83-6
Molecular Weight:
500.57
Formula:
C21H32N4O8S
Chemical Name:
2,5-dioxopyrrolidin-1-yl 3-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]propanoate
Smiles :
O=C1N[C@H]2CS[C@@H](CCCCC(=O)NCCOCCOCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1
InChiKey:
UCJSJBIJPAZUGU-AVYPCKFXSA-N
InChi :
InChI=1S/C21H32N4O8S/c26-16(4-2-1-3-15-20-14(13-34-15)23-21(30)24-20)22-8-10-32-12-11-31-9-7-19(29)33-25-17(27)5-6-18(25)28/h14-15,20H,1-13H2,(H,22,26)(H2,23,24,30)/t14-,15-,20-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Coenzyme FO} MedChemExpress|{Coenzyme FO} Anti-infection|{Coenzyme FO} Biological Activity|{Coenzyme FO} Description|{Coenzyme FO} supplier|{Coenzyme FO} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Pretomanid} MedChemExpress|{Pretomanid} Anti-infection|{Pretomanid} Protocol|{Pretomanid} In Vitro|{Pretomanid} custom synthesis|{Pretomanid} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23319057
Additional information:
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 596820-83-6|Molecular Weight: 500.57|Formula: C21H32N4O8S|Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]propanoate|Smiles: O=C1N[C@H]2CS[C@@H](CCCCC(=O)NCCOCCOCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1|InChiKey: UCJSJBIJPAZUGU-AVYPCKFXSA-N|InChi: InChI=1S/C21H32N4O8S/c26-16(4-2-1-3-15-20-14(13-34-15)23-21(30)24-20)22-8-10-32-12-11-31-9-7-19(29)33-25-17(27)5-6-18(25)28/h14-15,20H,1-13H2,(H,22,26)(H2,23,24,30)/t14-,15-,20-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|