Product Name :
CREB Recombinant Rabbit Monoclonal Antibody [SA04-04]
Predicted band size :
35 kDa
Observed band size :
42 kDa
Synonyms:
Active transcription factor CREB antibody cAMP response element binding protein 1 antibody cAMP response element binding protein antibody cAMP responsive element binding protein 1 antibody cAMP-responsive element-binding protein 1 antibody CREB antibody CREB-1 antibody CREB1 antibody CREB1_HUMAN antibody Cyclic AMP-responsive element-binding protein 1 antibody 展开
Function :
CREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements (CRE), thereby increasing or decreasing the transcription of the genes. CREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. Genes whose transcription is regulated by CREB include: c-fos, BDNF, tyrosine hydroxylase, numerous neuropeptides (such as somatostatin, enkephalin, VGF, corticotropin-releasing hormone), and genes involved in the mammalian circadian clock (PER1, PER2). CREB is closely related in structure and function to CREM (cAMP response element modulator) and ATF-1 (activating transcription factor-1) proteins. CREB has a well-documented role in neuronal plasticity and long-term memory formation in the brain and has been shown to be integral in the formation of spatial memory.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human CREB aa 250-290.{{Pertuzumab} site|{Pertuzumab} EGFR|{Pertuzumab} Technical Information|{Pertuzumab} Formula|{Pertuzumab} manufacturer|{Pertuzumab} Autophagy}
Species reactivity:
Human, Mouse, Zebrafish, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Coupling :
unconjugated
Clone number:
SA04-04
RRID:
AB_3069597
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{6-Thioguanine} medchemexpress|{6-Thioguanine} Deubiquitinase|{6-Thioguanine} Biological Activity|{6-Thioguanine} Description|{6-Thioguanine} custom synthesis|{6-Thioguanine} Cancer} Aliquot store at -20℃ or -80℃.PMID:23460641 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 35 kDa
Positive control :
HeLa cell lysate, A431 cell lysate, U-2 OS cell lysate, HEK-293 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, C6 cell lysate, PC-12 cell lysate, rat testis tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, zebrafish tissue lysates, Hela, human tonsil tissue, human lung carcinoma tissue, human breast carcinoma tissue, human thyroid tissue, human stomach carcinoma tissue, human pancreas tissue, mouse colon tissue, rat brain tissue, NIH/3T3, C6, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue.