Product Name :
COMP Mouse Monoclonal Antibody [A10H2]
Predicted band size :
83 kDa
Observed band size :
100 kDa
Synonyms:
cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) antibody Cartilage oligomeric matrix protein antibody Cartilage oligomeric matrix protein precursor antibody COMP antibody COMP_HUMAN antibody EDM 1 antibody EDM1 antibody EPD 1 antibody EPD1 antibody Epiphyseal dysplasia 1 antibody 展开
Function :
Cartilage oligomeric matrix protein (COMP), also known as thrombospondin-5, is an extracellular matrix (ECM) protein primarily present in cartilage. In humans it is encoded by the COMP gene. The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfide bonds. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). COMP is a marker of cartilage turnover. It is present in high quantities in fibrotic scars and systemic sclerosis, and it appears to have a role in vascular wall remodeling.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Synthetic peptide within human COMP aa 321-370.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
A10H2
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Abexinostat} web|{Abexinostat} Cell Cycle/DNA Damage|{Abexinostat} Technical Information|{Abexinostat} In stock|{Abexinostat} supplier|{Abexinostat} Autophagy} Aliquot store at -20℃.{{Cephalexin} MedChemExpress|{Cephalexin} Penicillin-binding protein (PBP)|{Cephalexin} Biological Activity|{Cephalexin} Purity|{Cephalexin} custom synthesis|{Cephalexin} Epigenetics} Avoid repeated freeze / thaw cycles.PMID:26895888
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 83 kDa
Positive control :
Mouse articular cartilage tissue lysate, Rat articular cartilage tissue lysate, mouse cartilage tissue, rat cartilage tissue.