Product Name :
ADAMTS13 Recombinant Rabbit Monoclonal Antibody [JG39-21]
Predicted band size :
Observed band size :
Synonyms:
A disintegrin and metalloproteinase with thrombospondin motifs 13 antibody A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 13 antibody A disintegrin like and metalloprotease with thrombospondin type 1 motif 13 antibody ADAM metallopeptidase with thrombospondin type 1 motif 13 antibody ADAM TS antibody ADAM-TS 13 antibody ADAM-TS13 antibody ADAMTS 13 antibody ADAMTS-13 antibody ADAMTS13 antibody 展开
Function :
ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting.{{Etrasimod} MedChemExpress|{Etrasimod} GPCR/G Protein|{Etrasimod} Purity & Documentation|{Etrasimod} Data Sheet|{Etrasimod} supplier|{Etrasimod} Autophagy} It is secreted in blood and degrades large vWf multimers, decreasing their activity.{{Islatravir} site|{Islatravir} HIV|{Islatravir} Protocol|{Islatravir} Description|{Islatravir} manufacturer|{Islatravir} Epigenetic Reader Domain} Glycosylated.PMID:24282960 O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human ADAMTS13 aa 71-124 / 1,427.
Species reactivity:
Human, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JG39-21
RRID:
AB_3070880
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size 154 kDa
Positive control :
SiHa cell lysate, PC-3M cell lysate, A549 cell lysate, human kidney tissue, rat kidney tissue, human liver tissue, human colon tissue.