Product Name :
NR 7h
Description:
NR 7h is a potent and selective p38α and p38β degrader that is active in vivo.
CAS:
Molecular Weight:
998.87
Formula:
C48H50BrF2N9O8
Chemical Name:
3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N-(4-(1-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-4-oxobutyl)-1H-1,2,3-triazol-4-yl)butyl)-4-methylbenzamide
Smiles :
CC1=CC=C(C=C1N1C(=O)C(Br)=C(C=C1C)OCC1=CC=C(F)C=C1F)C(=O)NCCCCC1=CN(CCCC(=O)NCCCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)N=N1
InChiKey:
BEMLUUUHZPFCBS-UHFFFAOYSA-N
InChi :
InChI=1S/C48H50BrF2N9O8/c1-28-13-14-30(24-38(28)59-29(2)23-39(43(49)48(59)67)68-27-31-15-16-32(50)25-35(31)51)44(63)54-21-4-3-9-33-26-58(57-56-33)22-8-12-40(61)53-20-6-5-19-52-36-11-7-10-34-42(36)47(66)60(46(34)65)37-17-18-41(62)55-45(37)64/h7,10-11,13-16,23-26,37,52H,3-6,8-9,12,17-22,27H2,1-2H3,(H,53,61)(H,54,63)(H,55,62,64)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{N6-Ethyladenosine} MedChemExpress|{N6-Ethyladenosine} Adenosine Receptor|{N6-Ethyladenosine} Protocol|{N6-Ethyladenosine} Data Sheet|{N6-Ethyladenosine} supplier|{N6-Ethyladenosine} Cancer}
Shelf Life:
≥12 months if stored properly.{{Glycocholic acid} medchemexpress|{Glycocholic acid} Endogenous Metabolite|{Glycocholic acid} Biological Activity|{Glycocholic acid} Description|{Glycocholic acid} manufacturer|{Glycocholic acid} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
NR 7h is a potent and selective p38α and p38β degrader that is active in vivo.|Product information|Molecular Weight: 998.87|Formula: C48H50BrF2N9O8|Chemical Name: 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N-(4-(1-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-4-oxobutyl)-1H-1,2,3-triazol-4-yl)butyl)-4-methylbenzamide|Smiles: CC1=CC=C(C=C1N1C(=O)C(Br)=C(C=C1C)OCC1=CC=C(F)C=C1F)C(=O)NCCCCC1=CN(CCCC(=O)NCCCCNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)N=N1|InChiKey: BEMLUUUHZPFCBS-UHFFFAOYSA-N|InChi: InChI=1S/C48H50BrF2N9O8/c1-28-13-14-30(24-38(28)59-29(2)23-39(43(49)48(59)67)68-27-31-15-16-32(50)25-35(31)51)44(63)54-21-4-3-9-33-26-58(57-56-33)22-8-12-40(61)53-20-6-5-19-52-36-11-7-10-34-42(36)47(66)60(46(34)65)37-17-18-41(62)55-45(37)64/h7,10-11,13-16,23-26,37,52H,3-6,8-9,12,17-22,27H2,1-2H3,(H,53,61)(H,54,63)(H,55,62,64)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 99.PMID:36014399 89 mg/mL(100 mM)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|