ADAMTS-2 Rabbit Polyclonal Antibody

Function :
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.{{Lonidamine} site|{Lonidamine} Parasite|{Lonidamine} Protocol|{Lonidamine} Formula|{Lonidamine} supplier|{Lonidamine} Epigenetics} Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase.{{EI1} web|{EI1} Histone Methyltransferase|{EI1} Biological Activity|{EI1} References|{EI1} supplier|{EI1} Autophagy} This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically