Product Name :
CLEC5A Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
C type lectin domain family 5 member A antibody C-type lectin domain family 5 member A antibody C-type lectin superfamily member 5 antibody CLC5A_HUMAN antibody CLEC5 A antibody CLEC5A antibody CLECSF 5 antibody CLECSF5 antibody MDL 1 antibody MDL-1 antibody 展开
Function :
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses.{{Regorafenib} medchemexpress|{Regorafenib} c-Kit|{Regorafenib} Protocol|{Regorafenib} In Vitro|{Regorafenib} manufacturer|{Regorafenib} Cancer} Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from mouse CLEC5A 101-190/190
Species reactivity:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit
Verify application:
WB, ELISA, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.{{Camidanlumab} site|{Camidanlumab} Interleukin Related|{Camidanlumab} Protocol|{Camidanlumab} Purity|{Camidanlumab} manufacturer|{Camidanlumab} Cancer} Avoid repeated freeze/thaw cycles.PMID:23664186 The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
22 KDa
Positive control :
Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U937 and MonoMac6, but not in cell lines of other origins. Expression is down-regulated when monocytes differentiate into dendritic cells.