Product Name :
NOD-IN-1
Description:
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 M and 6.45 M, respectively.
CAS:
132819-92-2
Molecular Weight:
343.40
Formula:
C18H17NO4S
Chemical Name:
ethyl 1-tosyl-1H-indole-2-carboxylate
Smiles :
CC1C=CC(=CC=1)S(=O)(=O)N1C2=CC=CC=C2C=C1C(=O)OCC
InChiKey:
OJMOGUKIYRAILM-UHFFFAOYSA-N
InChi :
InChI=1S/C18H17NO4S/c1-3-23-18(20)17-12-14-6-4-5-7-16(14)19(17)24(21,22)15-10-8-13(2)9-11-15/h4-12H,3H2,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{GSK1059615} MedChemExpress|{GSK1059615} PI3K/Akt/mTOR|{GSK1059615} Immunology/Inflammation|{GSK1059615} Protocol|{GSK1059615} Data Sheet|{GSK1059615} manufacturer}
Additional information:
NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.{{Zoledronic Acid} web|{Zoledronic Acid} Autophagy|{Zoledronic Acid} Technical Information|{Zoledronic Acid} In stock|{Zoledronic Acid} supplier|{Zoledronic Acid} Epigenetic Reader Domain} 74 M and 6.PMID:34337881 45 M, respectively.|Product information|CAS Number: 132819-92-2|Molecular Weight: 343.40|Formula: C18H17NO4S|Chemical Name: ethyl 1-tosyl-1H-indole-2-carboxylate|Smiles: CC1C=CC(=CC=1)S(=O)(=O)N1C2=CC=CC=C2C=C1C(=O)OCC|InChiKey: OJMOGUKIYRAILM-UHFFFAOYSA-N|InChi: InChI=1S/C18H17NO4S/c1-3-23-18(20)17-12-14-6-4-5-7-16(14)19(17)24(21,22)15-10-8-13(2)9-11-15/h4-12H,3H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 69 mg/mL(200.93 mM). Water: Insoluble.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Kecek Plesec K, et al. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.Products are for research use only. Not for human use.|