Product Name :
CIRBP Mouse Monoclonal Antibody [B3-E12]
Predicted band size :
Observed band size :
Synonyms:
A18 hnRNP antibody A18HNRNP antibody cirbp antibody CIRBP_HUMAN antibody CIRP antibody Cold inducible RNA binding protein antibody Cold-inducible RNA-binding protein antibody Glycine rich RNA binding protein antibody Glycine-rich RNA-binding protein CIRP antibody testicular tissue protein Li 39 antibody
Function :
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
B3-E12
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.{{PAC} web|{PAC} PROTAC|{PAC} Technical Information|{PAC} Data Sheet|{PAC} manufacturer|{PAC} Autophagy}
Storage buffer solution:
Purified antibody in PBS with 0.{{Teriflunomide} web|{Teriflunomide} Metabolic Enzyme/Protease|{Teriflunomide} Technical Information|{Teriflunomide} Description|{Teriflunomide} custom synthesis|{Teriflunomide} Autophagy} 05% sodium azide.PMID:24190482
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
19 kDa
Positive control :
Human CIRBP recombinant protein, CIRBP-hIgGFc transfected HEK293 cell lysate, SW480, PC-3, A431, U251 cell lysate, human bladder cancer tissue, human rectum cancer tissue.