Product Name :
CDK1 Recombinant Rabbit Monoclonal Antibody [SY26-02]
Predicted band size :
34 kDa
Observed band size :
34 kDa
Synonyms:
Cdc 2 antibody Cdc2 antibody CDC28A antibody CDK 1 antibody CDK1 antibody CDK1_HUMAN antibody CDKN1 antibody CELL CYCLE CONTROLLER CDC2 antibody Cell division control protein 2 antibody Cell division control protein 2 homolog antibody 展开
Function :
Cdk1 is a small protein (approximately 34 kilodaltons), and is highly conserved. Cdk1 is comprised mostly by the bare protein kinase motif, which other protein kinases share. Cdk1, like other kinases, contains a cleft in which ATP fits. When bound to its cyclin partners, Cdk1 phosphorylation leads to cell cycle progression.{{Evobrutinib} web|{Evobrutinib} Btk|{Evobrutinib} Technical Information|{Evobrutinib} In stock|{Evobrutinib} manufacturer|{Evobrutinib} Epigenetics} Given its essential role in cell cycle progression, Cdk1 is highly regulated. Most obviously, Cdk1 is regulated by its binding with its cyclin partners. Cyclin binding alters access to the active site of Cdk1, allowing for Cdk1 activity; furthermore, cyclins impart specificity to Cdk1 activity. At least some cyclins contain a hydrophobic patch which may directly interact with substrates, conferring target specificity. Furthermore, cyclins can target Cdk1 to particular subcellular locations.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human CDK1 aa 1-50 / 297.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP
Coupling :
unconjugated
Clone number:
SY26-02
RRID:
AB_3069770
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Ibuprofen} MedChemExpress|{Ibuprofen} COX|{Ibuprofen} Protocol|{Ibuprofen} In Vivo|{Ibuprofen} manufacturer|{Ibuprofen} Autophagy} Aliquot store at -20℃ or -80℃.PMID:24278086 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 34 kDa
Positive control :
HeLa cell lysate, Saos-2 cell lysate, Jurkat cell lysate, mouse spleen tissue lysate, HeLa, human breast cancer tissue, human tonsil tissue, human testis tissue, mouse testis tissue, rat testis tissue.