Product Name :
CDC123 Recombinant Rabbit Monoclonal Antibody [JE53-14]
Predicted band size :
Observed band size :
Synonyms:
C10orf7 antibody CD123_HUMAN antibody CDC123 antibody Cell division cycle 123 antibody Cell division cycle 123 homolog antibody Cell division cycle protein 123 homolog antibody D123 antibody HT 1080 antibody HT-1080 antibody Protein D123 antibody 展开
Function :
The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control.{{Streptomycin} web|{Streptomycin} Antibiotic|{Streptomycin} Purity & Documentation|{Streptomycin} In Vivo|{Streptomycin} supplier|{Streptomycin} Epigenetic Reader Domain} Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human CDC123 aa 1-120 / 336.{{γ-Aminobutyric acid} site|{γ-Aminobutyric acid} Metabolic Enzyme/Protease|{γ-Aminobutyric acid} Technical Information|{γ-Aminobutyric acid} Purity|{γ-Aminobutyric acid} manufacturer|{γ-Aminobutyric acid} Epigenetics}
Species reactivity:
Human, Mouse
Verify application:
WB, FC
Coupling :
unconjugated
Clone number:
JE53-14
RRID:
AB_3070997
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:23819239 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 39 kDa
Positive control :
K562 cell lysate, A549 cell lysate, F9.