Product Name :
CD98 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
4F2 antibody 4F2 cell surface antigen heavy chain antibody 4F2 cell-surface antigen heavy chain antibody 4F2 heavy chain antibody 4F2 heavy chain antigen antibody 4F2_HUMAN antibody 4F2hc antibody 4T2HC antibody Antigen defined by monoclonal antibody 4F2 heavy chain antibody Antigen identified by monoclonal antibodies 4F2 TRA1.10 TROP4 and T43 antibody 展开
Function :
Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer. The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and SLC7A8 to the plasma membrane and for channel activity. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. The heterodimer with SLC7A5/LAT1 may play a role in the transport of L-DOPA across the blood-brain barrier. May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier. The heterodimer with SLC7A5/LAT1 can mediate the transport of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from the C-terminal region of human SLC3A2.{{Mepolizumab (anti-IL5)} medchemexpress|{Mepolizumab (anti-IL5)} Interleukin Related|{Mepolizumab (anti-IL5)} Protocol|{Mepolizumab (anti-IL5)} Data Sheet|{Mepolizumab (anti-IL5)} manufacturer|{Mepolizumab (anti-IL5)} Epigenetics} AA range:491-540
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Salicylic acid} site|{Salicylic acid} Autophagy|{Salicylic acid} Biological Activity|{Salicylic acid} References|{Salicylic acid} custom synthesis|{Salicylic acid} Autophagy} Aliquot store at -20℃ or -80℃.PMID:24818938 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
69 kDa
Positive control :
B-cell lymphoma,Epithelium,Fibroblast,Liver,Lung,Mammary cancer,Pla