Product Name :
CD95 / Fas Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ALPS 1A antibody ALPS1A antibody APO 1 antibody Apo 1 antigen antibody APO 1 cell surface antigen antibody Apo-1 antigen antibody APO1 antibody Apo1 antigen antibody APO1 cell surface antigen antibody Apoptosis antigen 1 antibody 展开
Function :
Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immuno-surveillance against virus-infected or transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (also designated APO-1) and its ligand (FAS-L). The human FAS protein is a cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, certain of which undergo apoptosis in response to treatment with antibody to FAS.{{Fmoc-Cys(Trt)-OH} medchemexpress|{Fmoc-Cys(Trt)-OH} {Amino Acid Derivatives}|{Fmoc-Cys(Trt)-OH} Technical Information|{Fmoc-Cys(Trt)-OH} Purity|{Fmoc-Cys(Trt)-OH} custom synthesis|{Fmoc-Cys(Trt)-OH} Autophagy} These findings strongly imply that targeted cell death is potentially mediated by the intercellular interactions of FAS with its ligand or effectors, and that FAS may be critically involved in CTL-mediated cytotoxicity.{{Insulin lispro} site|{Insulin lispro} Biological Activity|{Insulin lispro} Purity|{Insulin lispro} supplier|{Insulin lispro} Epigenetics}
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
peptide
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, ICC, IP
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃
Storage buffer solution:
1.PMID:24103058 0 ml of PBS with
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
48 kDa
Positive control :
rat thymus tissue.