Product Name :
CD66b Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Carcinoembryonic antigen CGM6 antibody Carcinoembryonic antigen gene family member 6 antibody Carcinoembryonic antigen related cell adhesion molecule 8 antibody Carcinoembryonic antigen-related cell adhesion molecule 8 antibody CD 66b antibody CD 67 antibody CD66b antibody CD66b antigen antibody CD67 antibody CD67 antigen antibody 展开
Function :
Carcinoembryonic antigen-related cell adhesion molecule 8, also designated CD67, CD66b or nonspecific cross-reacting antigen (NCA-95), belongs to the human carcinoembryonic antigen (CEA) family. The CD67 antigen is encoded by the CEACAM8 (CGM6) gene, which is exclusively expressed in neutrophils and eosinophils. In neutrophils, the CEACAM8 gene is primarily detected in the secondary granules within the cytoplasm, but it can also be found in lower amounts on the plasma membrane. The amount of CD67 on the plasma membrane is up-regulated upon granulocyte activation. CD67 has been located on the surface of neutrophilic and eosinophilic granulocytes at late stages of differentiation. It exhibits heterophilic cell adhesion properties with CD66c, which is coexpressed with CD67 in granulocytes. CD67, which is attached to the membrane by a GPI-anchor, is expressed in leukocytes of chronic myeloid leukemia patients and bone marrow and in granulocytes in the spleen, thymus and lungs.Cimetidine
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human CD66b aa 1-250.AQC
Species reactivity:
Human
Verify application:
WB, IHC-P, mIHC, IF-Tissue
Coupling :
unconjugated
Clone number:
RRID:
AB_3071199
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:26780211 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 38 kDa
Positive control :
Human cervical cancer, human colon cancer tissue, human breast cancer tissue, human spleen tissue, human colon tissue, U937 cell lysate, A431 cell lysate, Daudi cell lysate.