Product Name :
CD21 Mouse Monoclonal Antibody [A4E5]
Predicted band size :
113 kDa
Observed band size :
160 kDa
Synonyms:
C3DR antibody CD 21 antibody CD21 antibody Complement C3d receptor antibody Complement component (3d/Epstein Barr virus) receptor 2 antibody Complement receptor type 2 antibody CR antibody Cr2 antibody CR2_HUMAN antibody CVID7 antibody 展开
Function :
CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes.SARS-CoV-2 S2 Protein (HEK293, His) The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner.Idarubicin hydrochloride On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate.PMID:24761411 Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Synthetic peptide within human CD21 aa 980-1033.
Species reactivity:
Human
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
A4E5
RRID:
AB_3071619
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG2b
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 113 kDa
Positive control :
Raji cell lysate, Jurkat cell lysate, human tonsil tissue, human spleen tissue, SW620, 293T.