Are discovered inside the neuronal cytoplasm of AD sufferers and are
Are found inside the neuronal cytoplasm of AD individuals and are composed of abnormally phosphorylated Tau protein. Tau hyperphosphorylation is the outcome of your aberrant activation of either kinases or phosphatases. One of essentially the most studied kinases, responsible for the phosphorylation on Tau protein at various residues, is GSK3-. The latter is ubiquitously expressed […]