2023 - epigenetics modulation frontier

SRPIN340

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. SRPIN340 CAS No. : 218156-96-8 Biological Activity：SRPIN340 is an ATP-competitive serine-arginine-rich protein kinase (SRPK) inhibitor, with a Ki of 0.89 μM for SRPK1. Research Area：Cancer Targets：SRPK|Virus Protease Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging […]

DB0614

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. DB0614 CAS No. : 2769753-47-9 Biological Activity：DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK, LCK, LIMK2, MAP3KH, MAPK8, MAPK9, NEK9, PLK4, PTK2B, SIK2, STK17A, STK17B, ULK1, ULK3, and WEE1. […]

NTRC-824

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. NTRC-824 CAS No. : 1623002-61-8 Biological Activity：NTRC-824 (Compound 5) is a potent, selective and neurotensin-like nonpeptide neurotensin receptor type 2 (NTS2) antagonist with an IC50 of 38 nM and a Ki of 202 nM. NTRC-824 is >150-fold selectivity for NTS2 over NTS1 (Ki >30 μM). […]

Enpp/Carbonic anhydrase-IN-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Enpp/Carbonic anhydrase-IN-1 Biological Activity：Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. […]

Cephalexin-d5

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Cephalexin-d5 CAS No. : 2101505-56-8 Biological Activity：Cephalexin-d5 is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and […]

Alizapride hydrochloride

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Alizapride hydrochloride CAS No. : 59338-87-3 Biological Activity：Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders[3]. Research Area：Cancer|Neurological Disease Targets：Dopamine Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library […]

SIRT1/2/3-IN-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. SIRT1/2/3-IN-1 CAS No. : 2413212-06-1 Biological Activity：SIRT1/2/3-IN-1 (compound 10) is a highly potent, selective and cell permeable inhibitor of SIRT1, SIRT2 and SIRT3 with IC50s of 0.54, 0.253, and 0.72 μM, respectively. SIRT1/2/3-IN-1 (compound 10) can be used for research of cancer. Targets：Sirtuin Related Small […]

MALAT1-IN-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. MALAT1-IN-1 CAS No. : 827327-28-6 Biological Activity：MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) . Research Area：Cancer Targets：Others Related […]

Sibiricose A1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Sibiricose A1 CAS No. : 139726-40-2 Biological Activity：Sibiricose A1is an oligosaccharide ester that can be found in Polygala tenuifolia. Research Area：Others Targets：Others Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Natural Product Library;Glycoside Compound Library;Phenols Library;Plant-Sourced Natural Product Library; Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole […]

γ-Secretase modulator 4

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. γ-Secretase modulator 4 CAS No. : 1420200-82-3 Biological Activity：γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.014 μM and 0.017 μM in human and mouse, respectively. Research Area：Neurological Disease Targets：γ-secretase Related Small Molecules:ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator […]