2023 - epigenetics modulation frontier

DPTIP

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. DPTIP CAS No. : 351353-48-5 Biological Activity：DPTIP is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM[2]. Research Area：Inflammation/Immunology Targets：Phospholipase Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Pyroptosis Compound Library;Exosomes Compound Library;Lipid Metabolism Compound […]

(S,R,S)-AHPC TFA

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. (S,R,S)-AHPC TFA CAS No. : 1631137-51-3 Biological Activity：(S,R,S)-AHPC (VH032-NH2) TFA is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). […]

pUL89 Endonuclease-IN-1

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. pUL89 Endonuclease-IN-1 CAS No. : 391680-92-5 Biological Activity：pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 value of 0.88 μM and has antiviral activitiy. Research Area：Infection Targets：CMV Related Small Molecules:Calcium trinatrium diethylenetriaminepentaacetic acid hydrate;Enocitabine;Fomivirsen sodium;Braco-19;Tricin;Ancitabine hydrochloride;Tomeglovir;Bisindolylmaleimide IV;Artemisone;SIRT1-IN-1;ML324;Cyclopropavir;B220;CEF20;FIT-039;Maribavir;Cyclic […]

ZJ43

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. ZJ43 CAS No. : 723331-20-2 Biological Activity：ZJ43 is a potent NAAG peptidase inhibitor, with an IC50 of 2.4 nM and a Ki of 0.8 nM. ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect […]

CP-20961

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. CP-20961 CAS No. : 35607-20-6 Biological Activity：CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[2]. Research Area：Infection|Inflammation/Immunology Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | […]

m-PEG21-OH

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. m-PEG21-OH Biological Activity：m-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Research Area：Cancer Targets：PROTAC Linkers Related Small Molecules:N-(Mal-PEG6)-N-bis(PEG7-TCO);Propargyl-PEG2-CH2COOH;NHS ester-PEG10-COOH;Tos-PEG5-Boc;Bis-PEG6-NHS ester;Azide-PEG12-alcohol;Fmoc-PEG6-NHS ester;Boc-C1-PEG3-C4-OBn;Boc-NH-PEG8-C2-Br;Propargyl-PEG14-Boc;Bromo-PEG3-THP;m-PEG8-Ms;Bis-PEG10-NHS ester;TCO-PEG3-acid;m-PEG8-DBCO;Azide-PEG6-Tos;Acid-PEG3-C2-Boc;m-PEG-mal (MW 2000);Benzyl-PEG7-t-butyl ester;Boc-Pip-alkyne-Ph-COOH;Biotin-PEG2-C6-azide;Bis-PEG4-acid;Active-mono-sulfone-PEG8-acid;Br-PEG6-C2-NHBoc;HO-PEG8-CH2COOH;NH2-PEG4-CH2CH2COOH;N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester;Bromoacetamido-PEG8-Boc;Carboxy-PEG2-sulfonic acid Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent […]

Gastrin I (1-14), human

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Gastrin I (1-14), human CAS No. : 100940-57-6 Biological Activity：Gastrin I (1-14), human is 1-14 fragment of human gastrin I peptide. Gastrin I is an endogenous, gastrointestinal peptide hormone. Gastrin is the major hormonal regulator of gastric acid secretion. Research Area：Endocrinology|Metabolic Disease Targets：Others Related Small […]

SR9186

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. SR9186 CAS No. : 1361414-26-7 Biological Activity：SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to […]

Antileishmanial agent-2

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. Antileishmanial agent-2 Biological Activity：Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells. Research Area：Infection Targets：Parasite Related Small Molecules:(+)-Isopulegol;SR9186;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251 Trending products：Recombinant Proteins | […]

KB SRC 4

Posted on January 16, 2023 by haoyuan2014

For research use only. We do not sell to patients. KB SRC 4 CAS No. : 1380088-03-8 Biological Activity：KB SRC 4 is a potent, and highly selective c-Src inhibitor, with a Ki of 44 nM and a Kd of 86 nM, and shows no inhibition on c-Abl up to 125 μM; KB SRC 4 has […]