(Z)-FeCP-oxindole

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(Z)-FeCP-oxindole

CAS No. : 1137967-28-2

Biological Activity:(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.

Research Area:Cancer

Targets:VEGFR

Related Small Molecules:VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;MAZ51;R1530;AZD2932;R916562;XL092;Tyrosine kinase-IN-1;DMH4;Bucillamine

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