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Vismodegib

CAS No. : 879085-55-9

Biological Activity：Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC₅₀ of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC₅₀ values of 3.0 μM and 1.4 μM, respectively^[2].

Research Area：Cancer

Targets：Autophagy|Hedgehog

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Targeted Therapy Drug Library ;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:RU-SKI 43;Dynarrestin;RL-0070933;SANT 2;Ciliobrevin D;TPB15;CUR61414;HSP70-IN-3;SANT-1;Hh-Ag1.5;SMANT hydrochloride;Robotnikinin;Ciliobrevin A;SMO-IN-2;RUSKI-201 dihydrochloride;JK184;MK-4101;3-epi-Vitamin D3;Neurodazine;TAK-441;Jervine;SMO-IN-3

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