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Trimetazidine dihydrochloride
CAS No. : 13171-25-0
Biological Activity：Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective drug, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor[2][3][4].
Research Area：Cardiovascular Disease
Targets：Autophagy
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;FDA-Approved Drug Library;Autophagy Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Rare Diseases Drug Library;Human Metabolite Library;
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