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TOPK-p38/JNK-IN-1
CAS No. : 2745108-35-2
Biological Activity：TOPK-p38/JNK-IN-1 (Compound B12) is an orally active TOPK-p38/JNK signaling pathway inhibitor with the IC50 value of 2.14 µM for NO production. TOPK-p38/JNK-IN-1 shows anti-inflammatory activities. TOPK-p38/JNK-IN-1 also inhibits phosphorylate downstream related proteins and avoids degradation of TOPK.
Research Area：Cancer
Targets：JNK
Related Small Molecules:Akt/NF-κB/JNK-IN-1;JNK3 inhibitor-2;JIP-1(153-163) TFA;JNK-IN-8;JNK3 inhibitor-4;Sesamolin;Astragaloside IV;Tomatidine;(-)-Zuonin A;JNK3 inhibitor-1;Polyphyllin I;IQ-3;MAPK-IN-1;CT1-3;SR-3306;JNK3 inhibitor-3;BI-78D3;DB07268;JNK3 inhibitor-5;Guggulsterone;Urolithin B;Loureirin B;JNK-IN-7;MPT0B392;TCS JNK 5a;Anisomycin;IMM-H007
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