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Tipranavir
CAS No. : 174484-41-4
Biological Activity:Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410 nM[2]. Tipranavir inhibits SARS-CoV-2 3CLpro activity[3].
Research Area:Infection
Targets:HIV|HIV Protease|SARS-CoV
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Antiviral Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Rare Diseases Drug Library;EMA-Approved Drug Library;Human Metabolite Library;
Related Small Molecules:ddCTP trisodium;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;SARS-CoV-2-IN-33;GRL-0496;Flavopiridol;Grazoprevir potassium salt;TAT (48-57);FGI-106 tetrahydrochloride;SARS-CoV-2-IN-19;Molnupiravir;(Z)-9-Propenyladenine;Apabetalone;SARS-CoV-2 Mpro-IN-3;MM3122;Decanoyl-RVKR-CMK TFA
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