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Teglarinad chloride
CAS No. : 432037-57-5
Biological Activity:Teglarinad chloride (GMX1777) is a prodrug of GMX1778 (a nicotinamide phosphoribosyl transferase inhibitor). Teglarinad chloride exhibits antitumor activity in mice can be attributed to inhibition of NAMPT. Teglarinad chloride also enhances radiation efficacy, mediated by interference with DNA repair and antiangiogenesis[2].
Research Area:Cancer
Targets:NAMPT
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Anti-Obesity Compound Library;
Related Small Molecules:CB 300919;GNE-617;NAMPT inhibitor-linker 2;NAMPT degrader-1;Nampt-IN-8;Nampt-IN-3;Nampt-IN-10 TFA;Nampt-IN-7;SBI-797812;LB-60-OF61;Nampt-IN-5;CB30865;GPP78;NAT;Nampt-IN-1;LB-60-OF61 hydrochloride;STF-118804;OT-82;CHS-828;Nampt-IN-9;(E)-Daporinad;GNE-618
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