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TCS-OX2-29
CAS No. : 372523-75-6
Biological Activity：TCS-OX2-29 is a potent, high affinities and selective orexin-2 receptor (OX2R) antagonist with an IC50 value of 40 nM and a pKI value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX2 over OX1[2].
Research Area：Cancer|Endocrinology
Targets：Orexin Receptor (OX Receptor)
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Anti-Cancer Compound Library;Endocrinology Compound Library;
Related Small Molecules:MK-3697;JNJ-54717793;IPSU;Seltorexant hydrochloride;Orexin B, rat, mouse;SB-649868;Orexin A (human, rat, mouse) (acetate);SB-408124 Hydrochloride;OX2R-IN-1;EMPA;Orexin B, human;SB-334867 free base;MK-1064;Almorexant-13C,d3;YNT-185 dihydrochloride;Orexin 2 Receptor Agonist;[Ala11,D-Leu15]-Orexin B(human);Suntinorexton;Almorexant;SB-674042;Filorexant;Orexin receptor antagonist 4;OXA(17-33) TFA;Lemborexant;Danavorexton
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