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Seviteronel
CAS No. : 1610537-15-9
Biological Activity:Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition.
Research Area:Cancer
Targets:Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;Targeted Diversity Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil;Cholesterol 24-hydroxylase-IN-1;TMS;Harmalol hydrochloride;Olivetol
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