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ROS-ERS inducer 1

Biological Activity：ROS-ERS inducer 1 is a type II ICD (immunogenic cell death) inducer. ROS-ERS inducer 1 is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. ROS-ERS inducer 1 successfully induces endoplasmic reticulum stress (ERS) accompanied by reactive oxygen species (ROS) generation and finally lead to the release of damage-associated molecular patterns (DAMPs) in HCC cells. ROS-ERS inducer 1 displays much higher anticancer activities than Cisplatin.

Research Area：Cancer

Targets：Reactive Oxygen Species

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Chitoheptaose heptahydrochloride;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor 3;CYPMPO;Antioxidant agent-5;Glucosamine-13C hydrochloride;L-Ascorbic acid sodium salt;D-Isofloridoside;L-Carnitine-d3 hydrochloride;Licochalcone D;Euparin;RH-EDA;1,3-Dicaffeoylquinic acid;Antitumor agent-68;Echinocystic acid;Glucosamine-13C6,15N hydrochloride;PI3Kα-IN-8;Maresin 1-d5;Ecabet sodium;Ethoxyquin;Eugenol-d3;Rifamycin S;AKBA;L-Theanine;Chol-CTPP

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