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Roflumilast
CAS No. : 162401-32-3
Biological Activity：Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.
Research Area：Inflammation/Immunology
Targets：Phosphodiesterase (PDE)|RSV
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Antiviral Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Neurodegenerative Disease-related Compound Library;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Antidepressant Compound Library;EMA-Approved Drug Library;Human Metabolite Library;
Related Small Molecules:Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;ATX inhibitor 22;Carbazeran citrate;Bay 60-7550;BC11-38;Quercetin pentaacetate;Deltarasin hydrochloride;Glaucine;Ziritaxestat;Udenafil-d7;D159687;ITI-214;PDE10-IN-5;RSV604 (R enantiomer);ICI 153110;Furamidine dihydrochloride;ML-030;PDE4-IN-10;Mirodenafil-d7 dihydrochloride;PDE1-IN-4;PDE4B-IN-3;Cirsimarin;PF-03049423;IBMX
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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