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Ro 5212773-d5
CAS No. : 2733160-94-4
Biological Activity:Ro 5212773-d5 (EPPTB-d5) is the deuterium labeled Ro 5212773. Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids[2].
Research Area:Neurological Disease
Targets:Trace Amine-associated Receptor (TAAR)
Related Small Molecules:RO5166017;RO5263397;Ro 5212773;RO5256390;Ralmitaront
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