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RI-1
CAS No. : 415713-60-9
Biological Activity：RI-1 is a RAD51 inhibitor, with IC50s ranging from 5 to 30 μM. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319. RI-1 inactivates RAD51 by directly binding to a protein surface that serves as an interface between protein subunits in RAD51 filaments. RI-1 can disrupt homologous recombination in human cells.
Research Area：Cancer
Targets：RAD51
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-Breast Cancer Compound Library;
Related Small Molecules:RAD51-IN-6;Homologous recombination-IN-1;RAD51 Inhibitor B02;Amuvatinib hydrochloride;RI-2;RAD51-IN-5;Bractoppin;RS-1;RAD51-IN-3;RI(dl)-2 TFA;RAD51-IN-8;RAD51-IN-7;CAM833;IBR2;RAD51-IN-2;RAD51-IN-4;RAD51-IN-1
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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