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RG7112
CAS No. : 939981-39-2
Biological Activity：RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2.
Research Area：Cancer
Targets：MDM-2/p53|E1/E2/E3 Enzyme
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Ubiquitination Compound Library;Ferroptosis Compound Library;Pyroptosis Compound Library;Orally Active Compound Library;Chemical Probe Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:UBE2T/FANCL-IN-1;MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;DI-1859;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Teslexivir;TRAF6 peptide;Tenovin-6;PK11007;AM-8735;NAcM-OPT;GN25;RO-5963;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide
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