Proglumetacin

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Proglumetacin

CAS No. : 57132-53-3

Biological Activity:Proglumetacin is an orally active and potent cyclo-oxygenase inhibitor. Proglumetacin can inhibits SARS-CoV Mpro (main protease of the SARS-CoV-2), with an AC50 of 8.9 μM (activity concentration at half maximal activity). Proglumetacin has anti-inflammatory activity, can be used for inflammation (such as Rheumatoid arthritis, and Allergic air pouch inflammation) research[1][2][3].

Research Area:Inflammation/Immunology

Targets:COX|SARS-CoV

Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;Ampyrone;COX-2-IN-24;SARS-CoV-2-IN-33;GRL-0496;Zaltoprofen-d7;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Ketotifen fumarate;Asaraldehyde;(-)-Epicatechin;SARS-CoV-2-IN-16;Thapsigargin;20(S)-Ginsenoside Rg3;Ginsenoside Rd;INSCoV-614(1B);Nimesulide D5;COX-2/5-LOX-IN-1

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