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Pramipexole dihydrochloride
CAS No. : 104632-25-9
Biological Activity：Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson’s disease (PD) and restless legs syndrome (RLS)[2][3].
Research Area：Neurological Disease
Targets：Dopamine Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;CNS-Penetrant Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;EMA-Approved Drug Library;Human Metabolite Library;
Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 TFA;Sulpiride;(Rac)-Razpipadon;Clebopride malate;WAY-100635;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Itopride-d6 hydrochloride;ONC206;Brexpiprazole S-oxide;cis-(Z)-Flupentixol dihydrochloride;D4R antagonist-1;U91356
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