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PF 05089771
CAS No. : 1235403-62-9
Biological Activity：PF 05089771 is a potent, orally active and selective arylsulfonamide Nav1.7 inhibitor, with IC50 values of 11 nM, 12 nM, 13 nM, 171 nM and 8 nM for hNav1.7, cynNav1.7, dogNav1.7, ratNav1.7, and musNav1.7, respectively. PF 05089771 is under the study for pain and diabetic neuropathy[2].
Research Area：Neurological Disease
Targets：Sodium Channel
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library; Orally Active Compound Library;Neuroprotective Compound Library;Targeted Diversity Library;Sodium Channel Blocker Library;
Related Small Molecules:Lu AE98134;Zandatrigine;Veratridine;Brompheniramine-d6 maleate;GX-674;Dibucaine;Sodium Channel inhibitor 2;3-Deoxyaconitine;20(S)-Ginsenoside Rg3;Tocainide hydrochloride;Licarbazepine-d4-1;Metaflumizone-d4;β-Pompilidotoxin;Nav1.1 activator 1;ICA-121431;Brompheniramine maleate;ABBV-318;DPI 201-106;TC-N 1752
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