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PBIT
CAS No. : 2514-30-9
Biological Activity：PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1) histone demethylase with an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC50s of 6 μM and 4.9 μM, respectively.
Research Area：Cancer
Targets：Histone Demethylase
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Transcription Factor-Targeted Library;
Related Small Molecules:Bomedemstat ditosylate;LSD1/ER-IN-1;JQKD82;KDOAM-25 citrate;GSK-J1 lithium salt;S2116;LSD1-IN-16;TAK-418;NCGC00247743;DS17701585;KDM2B-IN-3;S2101;LSD1/2-IN-3;KDM5-IN-1;GSK467;S2157;PFI-90;FY-56;Eicosapentaenoic Acid;LSD1-IN-20;KDM5A-IN-1;Bizine;Procaine-d4 hydrochloride
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