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Pasireotide
CAS No. : 396091-73-9
Biological Activity：Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity[2][3].
Research Area：Cancer|Endocrinology
Targets：Somatostatin Receptor
Related Small Molecules:Cortistatin 29;L-803087 TFA;SSTR5 antagonist 1;J-2156;CYN 154806;Cortistatin-14 TFA;SSTR4 agonist 3;AGI-41998;MAT2A-IN-3;Onzigolide;MAT2A-IN-1;BIM-23056;Angiopeptin;Nendratareotide;BIM-23190 hydrochloride;CH 275;MAT2A-IN-2;Paltusotine;SSTR4 agonist 2
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