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Obatoclax
CAS No. : 803712-67-6
Biological Activity:Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2[2]. Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity[3][4].
Research Area:Cancer|Infection
Targets:Parasite|Autophagy|Bcl-2 Family
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