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Nebicapone

CAS No. : 274925-86-9

Biological Activity：Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson’s disease.

Research Area：Metabolic Disease

Targets：COMT

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Rare Diseases Drug Library;Protein-protein Interaction Inhibitor Library;Human Metabolite Library;

Related Small Molecules:Nitecapone;hMAO-B/MB-COMT-IN-2;Opicapone;Flopropione;Rosmarinic acid;5-Hydroxyferulic acid;Ro 41-0960;hMAO-B/MB-COMT-IN-1

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