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MW-150
CAS No. : 1628502-91-9
Biological Activity：MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia.
Research Area：Inflammation/Immunology|Neurological Disease
Targets：Autophagy|p38 MAPK
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Clinical Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:SB-747651A dihydrochloride;Dehydrocorydaline;SKF-86002 dihydrochloride;Pexmetinib;SB 242235;TA-01;Anti-inflammatory agent 7;VX-702;R1487 Hydrochloride;MBP MAPK Substrate;Isoliquiritin apioside;Sesamolin;MAPK13-IN-1;PF-05381941;Semapimod tetrahydrochloride;SD-169;Skatole;BMS-582949 hydrochloride;Gypenoside L;Dilmapimod;Pamapimod;Andrograpanin;MKK7-COV-9;AMG-47a;Kaempferol-3-O-glucorhamnoside;SB 202190 hydrochloride
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