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MRT-10

CAS No. : 330829-30-6

Biological Activity：MRT-10 is a seven-transmembrane receptor smoothened (Smo) antagonist with an IC₅₀ of 0.65 μM in the micromolar range in various Hedgehog (Hh) assays. MRT-10 binds to the Smo receptor at the level of the Bodipycyclopamine binding site. MRT-10 can be used for the research of cancer^[2].

Research Area：Cancer

Targets：Smo

Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;

Related Small Molecules:Saikosaponin B1;LEQ506;RL-0070933;20(S)-Hydroxycholesterol;Sonidegib;PF-5274857 hydrochloride;MRT-83 hydrochloride;TPB15;CUR61414;SANT-1;SAG-d3;SMANT hydrochloride;BMS-833923;SMO-IN-2;SMO-IN-1;IHR-1;Purmorphamine (GMP);IHR-Cy3;MRT-14;MK-4101;SAG hydrochloride;DY131

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