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MPO-IN-1

CAS No. : 2471981-21-0

Biological Activity：MPO-IN-1 is a potent, orally active, and irreversible indole-containing inhibitor of myeloperoxidase (MPO). MPO-IN-1 has IC₅₀s of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively. MPO-IN-1 inhibits MPO activity in an acute mouse model of inflammation.

Research Area：Inflammation/Immunology

Targets：Glutathione Peroxidase

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Anti-Cancer Metabolism Compound Library;

Related Small Molecules:HLF1-11;MPO-IN-28;Verdiperstat;MPO-IN-4;Mitiperstat;Tinoridine hydrochloride;PF-06282999;MPO-IN-3;BCP-T.A;4-Aminobenzohydrazide;MPO-IN-5;GPX4-IN-3;ML-210;PKUMDL-LC-101-D04;AZD5904;JKE-1674;RSL3;PF-1355;N-Acetyl lysyltyrosylcysteine amide;ML162;NBDHEX;JKE-1716

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