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MI-136
CAS No. : 1628316-74-4
Biological Activity:MI-136 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors[2].
Research Area:Cancer
Targets:Epigenetic Reader Domain|Androgen Receptor|Apoptosis
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Covalent Screening Library;Reprogramming Compound Library;Anti-Blood Cancer Compound Library;Transcription Factor-Targeted Library;Protein-protein Interaction Inhibitor Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;RVX-297;Lobetyolin;VPC-14449;BRD4 Inhibitor-19;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;UNC6349 (Ket2);Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9
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