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LDHA/PDKs-IN-2
CAS No. : 2490699-44-8
Biological Activity：LDHA/PDKs-IN-2 (compound 20k) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 1.6 and 0.7 μM, respectively. LDHA/PDKs-IN-2 reduces A549 cell proliferation with an EC50 of 15.7 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-2 has the potential for the research of cancer diseases.
Research Area：Cancer
Targets：PDK-1
Related Small Molecules:MP7;PS47;CRTh2 antagonist 3;Polyphyllin I;BX-320;(R)-PS210;BX517;LDHA/PDKs-IN-1;BX-912;BX795;GSK2334470;PDK1-IN-RS2
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