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KRH-3955 hydrochloride

CAS No. : 2253744-59-9

Biological Activity：KRH-3955 hydrochloride is an orally bioavailable CXCR4 antagonist. KRH-3955 hydrochloride inhibits SDF-1α binding to CXCR4 with an IC₅₀ of 0.61 nM. KRH-3955 hydrochloride is also a highly potent and selective inhibitor of X4 HIV-1, with an EC₅₀ of 0.3 to 1.0 nM.

Research Area：Infection|Inflammation/Immunology

Targets：CXCR|HIV

Related Small Molecules:Nicotinamide N-oxide;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;CXCR4 antagonist 2;Flavopiridol;AMG 487 (S-enantiomer);TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;CXCR4 antagonist 6;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine

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