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KDOAM-25 citrate
CAS No. : 2448475-08-7
Biological Activity:KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 citrate increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells.
Research Area:Cancer
Targets:Histone Demethylase
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Transcription Factor-Targeted Library;Targeted Diversity Library;
Related Small Molecules:Bomedemstat ditosylate;LSD1/ER-IN-1;PBIT;JQKD82;GSK-J1 lithium salt;S2116;LSD1-IN-16;TAK-418;NCGC00247743;DS17701585;KDM2B-IN-3;S2101;LSD1/2-IN-3;KDM5-IN-1;GSK467;S2157;PFI-90;FY-56;Eicosapentaenoic Acid;LSD1-IN-20;KDM5A-IN-1;Bizine;Procaine-d4 hydrochloride
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